Everything Epigenetics
Don’t understand epigenetics? Don’t worry. There was a time when genetic analysis was hardly known or understood. Now, genetic analysis is performed by thousands of companies and your full genome can be decoded for less than $100. Epigenetics is how your behaviors change your outcome. Epigenetics gives us knowledge on how to change your life, and the ability to read biology to understand your current health status. You ARE in control. Your host, Hannah Went, is here to discuss the insights which can improve your life and health. She is here to bring you Everything Epigenetics, simplified.
Episodes
33 episodes since 2022
The Future of Kidney Health: How Dr. Charles Breeze Is Changing the Game with Epigenetics
In this week’s episode of the Everything Epigenetics podcast, I’m joined by Dr. Charles Breeze, an expert in computational epigenetics. We talk about his inspiring journey into the field of epigenetics, his trailblazing research on kid...
September 11, 2024
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Season 2
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Episode 9
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44:35
Alzheimer’s Disease as an Epigenetic Disease with Dr. David Katz
Alzheimer’s disease is a devastating neurodegenerative condition that slowly erodes memory, cognitive function, and the ability to perform even the simplest tasks. It’s heartbreaking not only for those diagnosed but also for their loved ones as...
August 28, 2024
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Season 2
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Episode 8
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56:40
The Power of Single-Cell Epigenetic Profiling with Alex Trapp
In this week’s episode of the Everything Epigenetics podcast, Hannah Went sits down with Alex Trapp, a computational biologist deeply involved in aging research. The two explore the cutting-edge development of single-cell epigenetic clocks and ...
August 14, 2024
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Season 2
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Episode 7
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49:16
Development and Application of Epigenetic Predictors with Dr. Varun Dwaraka
The development and application of epigenetic predictors of health is revolutionizing the way we understand and approach personalized medicine. These predictors, derived from analyzing DNA methylation patterns, provide a powerful tool for asses...
July 31, 2024
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Season 2
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Episode 6
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53:44
Unraveling the Complexity of Epigenetics in the Brain with Dr. Esther Walton
In Europe, people aged 65 typically spend about half of their remaining years managing disabilities. Much of the existing research on aging has predominantly focused on identifying "cures" rather than exploring strategies for healthy aging. Dr....
July 17, 2024
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Season 2
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Episode 5
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51:03
Epigenetic Regulation of Immunity with Dr. Andrew DiNardo
The immune system adapts to various threats through innate and adaptive responses, utilizing epigenetic mechanisms to regulate gene activity without changing DNA sequences. These mechanisms help maintain long-term immune phenotypes, allowing th...
July 03, 2024
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Season 2
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Episode 4
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44:19
Traumas Epigenetic Impact on Mental Disorders with Dr. Janitza Montalvo-Ortiz
In this week’s episode of Everything Epigenetics, I am joined by Dr. Janitza Montalvo-Ortiz, Assistant Professor of Psychiatry at Yale University, who shares her journey into the world of epigenetics and psychiatry. Dr. Montalvo-Ortiz e...
June 19, 2024
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Season 2
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Episode 3
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57:58
A therapeutic trip: From experience to epigenome with Dr. Candace Lewis
We are entering a new phase of understanding how our social environments affect our biology, particularly how they influence the genes involved in brain development and function. This knowledge helps us see how experiences like stress, trauma, ...
June 05, 2024
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Season 2
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Episode 2
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54:50
Personalized Nutrition and Epigenetics with Dr. Lucia Aronica
Personalized nutrition tailors dietary recommendations to an individual's unique biological needs, factoring in genetics, lifestyle, and health conditions to optimize health, prevent disease, and maintain overall well-being. Central to this app...
May 22, 2024
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Season 2
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Episode 1
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54:01
Epigenetic Gestational Age Prediction with Kristine Løkås Haftorn
Determining a newborn's due date traditionally relies on maternal reports of the last menstrual period and ultrasound scans. These conventional approaches can lead to uncertainties, especially when it comes to identifying deviations fro...
February 07, 2024
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Season 1
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Episode 24
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56:24
Causal Epigenetic Age Uncouples Damage and Adaptation with Kejun (Albert) Ying
Machine learning models that use DNA markers can estimate the age of biological samples. However, understanding why these markers change with age is challenging because it's hard to prove that these changes cause aging-related traits. I...
January 24, 2024
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Season 1
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Episode 23
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46:44
The Importance of the Imprintome with Dr. Randy Jirtle
The idea of the impintome is still foreign to many people. So, let’s start with a simple explanation.For the majority of genes, we inherit two functional copies—one from our mother and one from our father. However, imprinted genes follo...
January 10, 2024
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Season 1
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Episode 22
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54:51
Integrating Epigenetics into the Social Models of Heath Disparities with Dr. Lauren Schmitz
Did you know that the Great Depression—the worst economic downturn in US history—impacted how fast individuals aged biologically decades later according to their epigenetic aging profiles?!Yep… you read that right. Results ...
December 27, 2023
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Season 1
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Episode 21
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52:03
Prioritizing Your Health Investment with Dr. Jeoff Drobot
I always have a great time chatting with Dr. Jeoff Drobot, and in this podcast he doesn’t disappoint. He is an expert in “age accounting” and often speaks about biological age in terms of environmental debits and credits..W...
December 13, 2023
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Season 1
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Episode 20
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54:22
Unlocking the Epigenome from a Single Drop of Blood with Dr. Toinét Cronjé
In this week’s Everything Epigenetics episode, I speak with Dr. Toinét Cronjé about what epigenetics can do for the field of epidemiology. Epidemiology is the study of the distribution and determinants of health-related states or e...
November 29, 2023
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Season 1
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Episode 19
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49:13
Tracking and Measuring Biomarkers to Maximize Longevity with Dr. Michael Lustgarten
In this week's Everything Epigenetics episode, I speak with Michael Lustgarten on tracking and measuring biomarkers to maximize longevity. His long-standing goal is to live longer than everyone that has ever lived. To do that, he plans on using...
November 15, 2023
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Season 1
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Episode 18
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1:03:33
Methylation Risk Scores with Dr. Mike Thompson
You may be familiar with polygenic risk scores (PRS), but have you ever heard of methylation risk scores (MRS)? MRS are crucial to understand, as they’re a tool that quantifies DNA methylation levels at specific genomic regions linked t...
November 01, 2023
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Season 1
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Episode 17
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1:02:09
The Role of Epigenetics in Functional Medicine with Dr. Jeffrey Bland
In this Everything Epigenetics episode, Dr. Jeffrey Bland and I discuss his significant contributions to functional medicines and how he has shaped this field. We also define functional medicine as a multidisciplinary approach that draws on the...
September 27, 2023
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Season 1
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Episode 16
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56:12
Assessing the Reproducibility and Integrity of DNA Methylation with Dr. Karen Sugden
The reliability of testing epigenetic DNA methylation using Illumina beadchips is of paramount importance due to the specific intricacies of this technology. Illumina beadchips are widely used platforms for high-throughput epigenet...
September 13, 2023
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Season 1
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Episode 15
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58:08
MOSAIC: Multi-Organ Scores of Aging across Integrated Components with Raghav Sehgal
Various aging clocks have been developed to quantify the aging process and predict age-related diseases. These biological age clocks are powered by different types of omics data and clinical biomarkers, and they’re especially useful fo...
August 30, 2023
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Season 1
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Episode 14
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51:55
Personalized Biomarkers to Predict Surgery Outcomes with Dr. Christopher Ames
Risk stratification in surgery is a crucial aspect of modern medical practice that involves assessing the potential risks and benefits associated with a surgical procedure for an individual patient. The goal is to optimize patient outcomes and ...
August 16, 2023
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Season 1
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Episode 13
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51:27
Reduce Your Biological Age in Just 8-Weeks with Dr. Kara Fitzgerald
Dr. Kara Fitzgerald's work in epigenetics revolves around the concept of "nutrigenomics" and "nutrigenetics," which are areas that investigate how nutrients and dietary factors can influence gene expression and how an individual's genetic makeu...
August 02, 2023
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Season 1
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Episode 12
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43:42
A Deeper Dive into DunedinPACE with Dr. Daniel Belsky
According to Dr. Daniel Belsky at Columbia University, there are three limitations of epigenetic biological age clocks:1. Mortality selection Essentially, biological age measures may underestimate true aging because older par...
July 19, 2023
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Season 1
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Episode 11
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52:37
How Fit Are You According to Your DNA? With Kristen McGreevy
As we age, physical fitness tends to decline. This decline can be attributed to various factors such as changes in body composition, reduced muscle mass and strength, decreased flexibility, and diminished cardiovascular endurance. Additionally,...
July 05, 2023
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Season 1
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Episode 10
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49:08
Predicting Mental Illnesses Using Epigenetics with Dr. Zachary Kaminsky
According to the National Institute of Mental Health, approximately 20% of adults (around 51.5 million people) experience a mental illness each year. I believe that is 51.5 million people too many!There is a HUGE need for the ability to...
June 21, 2023
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Season 1
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Episode 9
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50:09